Custom Oligonucleotides

SBS has synthesized millions of high-quality oligonucleotides for researchers since it was founded in 1994. The oligos have been applied in almost all fields of molecular biology, and have become the top choice for researchers.


To meet the increasing market demand, we have introduced the most advanced high-throughput synthesizers, which provide computer-controlled oligo synthesis, cleavage, and deprotection in a parallel-processing format. Our oligos are synthesized with a typical coupling efficiency of 99% and purified by QPC free of charge. PAGE  purification is also available with additional charge. The high coupling efficiency of our synthesis technology allows efficient synthesis of oligos up to 120 bases. In addition, a variety of modifications are available. Every oligo is analyzed by PAGE to check oligo quality. Malidi-Tof Mass QC is also employed to examine the oligos randomly at our facility. Now we are one of the leading companies in DNA synthesis in China.


Notes: All of the yields indicated below are after QPC, PAGE  purification.


Standard Oligos


Yield

Price (US$/base)

Working days

2 OD

0.20

5 OD

0.25

10 OD

0.32

1~2 days

30 OD

0.58

50 OD

0.83

100 OD

1.50


l  The price is only for oligos shorter than 60 mer.


Long Oligos


Length

Yield

Price (US$/base)

2 OD

0.43

5 OD

0.63

60~100 mer

10 OD

0.97

30 OD

2.67

50 OD

3.67

l Turn-around time is about 2-3 working days.

Phosphorothioate Oligos (S-Oligo)


5 OD (US$/bond)

10 OD (US$/bond)

30 OD (US$/bond)

50 OD (US$/bond)

100 OD (US$/bond)

0.53

0.80

2.00

2.67

4.67

l   S-oligo is charged per bond

l   Turn-around time is about 2-3 working days.


Modified oligos


Modification

2 OD (US$)

5 OD (US$)

10 OD (US$)

dInosine

10.00

13.00

17.00

dUridine

10.00

13.00

17.00

5-Methyl dC

13.00

20.00

27.00

O4-Me-dT

13.00

20.00

27.00

5’-Amino Linker C6

13.00

20.00

27.00

5’-Phosphorylation

27.00

33.00

47.00

5’-Biotin

27.00

33.00

47.00

5’-Thiol Modifier C6 S-S

27.00

33.00

47.00

3’-dInosine

10.00

13.00

17.00

3’-Amino Linker C7

27.00

33.00

47.00

3’-Phosphorylation

27.00

33.00

47.00

3’-Biotin

27.00

33.00

47.00

3’-Thiol Modifier C6 S-S

27.00

33.00

47.00


l   Turn-around time is about 2-3 working days.

l   Other modifications are available upon request.


Fluorescent Oligos


Fluorophores

2 OD (US$)

5 OD (US$)

10 OD (US$)

5’-FAM

40.00

47.00

67.00

5’-HEX

53.00

67.00

100.00

5’-TET

53.00

67.00

100.00

5’-Cy3 (Quasar 570)

127.00

160.00

267.00

5’-Cy5 (Quasar 670)

127.00

160.00

267.00

5’-TAMRA

67.00

80.00

107.00

5’-JOE

80.00

95.00

120.00

3’-FAM

40.00

47.00

  67.00

3’-TAMRA

53.00

67.00

100.00

3’-Dabcyl

53.00

67.00

100.00

3’-BHQ-1

53.00

67.00

100.00

3’-BHQ-2

53.00

67.00

 100.00

3’-BHQ-3

53.00

67.00

 100.00


l   Turn-around time is about 3-4 working days.

l  Other labelings are available upon request.


Oligo Purification


QUANTITY

QPC

PAGE (US$/oligo)

HPLC (US$/oligo)

2 OD

Free

10.00

10.00

5 OD

Free

15.00

15.00

10 OD

Free

30.00

30.00

30 OD

Free

75.00

75.00

50 OD

Free

90.00

90.00

100 OD

Free

120.00

120.00


l   QPC purification is only for < 60 mer standard oligos and S-oligos.

l   Long oligos (≥ 60 mer) should be PAGE purified.

l   Modified oligos should be PAGE or HPLC purified.





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