Synthetic modified sgRNAs

CRISPR/Cas9 genome editing technology is powerful for genome engineering like gene knock-ins and knock-outs. Genome engineering using synthetic sgRNAs yields more efficient and consistent editing results than any other types of guide RNA.

With excellent sgRNA synthesis and purification technology, we provide high-quality synthetic sgRNAs, which can be applied in various genome engineering. Our exclusive long-chain RNA synthesis technology can support around 100nt sgRNA synthesis. Normally we would provide 2'-O-methyl 3' phosphorothioate modifications in the first and last 3 nucleotides but we can also provide other types of customized modifications.

Features:

● Our professional sgRNA synthesis and purification technology will make your experiment more likely to be successful.

● We provide high precision mass spectrometry reports.

● We can ensure single main peak and theoretical molecular weight consistent with the detected molecular weight.

● The estimated purity showed in MS data  is greater than 90%.

Pricing:

  *Please inquire for larger scales.

Storage:

We recommend that sgRNA should be stored at -20℃ in either dry powder or solution state. sgRNA in solution state should also be avoided from repeated freezing and thawing.