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Description
Compared with other Cas proteins, the molecular weight of Cas14 protein is generally smaller (400-700aa). Similar to Cas12, Cas14a1 can also bind the target nucleic acid and activate its ssDNA trans clevage activity, so it is can be applied to the molecular detection of target nucleic acid. However, unlike Cas12, there is no PAM binding requirement for Cas14a1. Also, Cas14a1 cleaves only single-stranded DNA (ssDNA) and not double-stranded DNA or single-stranded RNA.
Applications
lReal-time Fluorescent Detection
lColloidal gold chromatography
lGene editing
lMolecular diagnosis
Storage
Minimum shelf life is 1 year at -20°C.
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